of April 20 , 2017 . This information is current as Expression by IL - 27 Generation with Enhanced Granzyme B T Cell + Augmentation of Effector CD 8 Yoshimoto

This information is current as Expression by IL - 27 Generation with Enhanced Granzyme B T Cell + Augmentation of Effector CD 8 Yoshimoto

سلول‌های T تنظیمی: انواع، تولید و عملکرد

T lymphocytes have been characterized to different subsets such as cytotoxic T, Thelper1 (Th1), Th2, Th3, Th9, Th17, and regulatory T cells. Each of these subsets have specific function which distinct them from other lymphocytes. Regulatory T lymphocytes are effective cells in immune system that play an important role in cancers, autoimmune and infectious diseases. Two main subsets of regulator...

STAT3 governs hyporesponsiveness and granzyme B-dependent suppressive capacity in human CD4+ T cells

Signal transducer and activator of transcription 3 (STAT3) integrates key signals of cell surface immune receptors, yet its precise role in cluster of differentiation (CD)4(+) T cells is not well-established. Current research has indicated T-helper cell 17-inducing roles but also tolerogenic roles. To address this issue, human T cells were transduced with the constitutively active STAT3 mutant ...

Interaction of perforin and granzyme B and HTLV-1 viral factors is associated with ATL development

Objective(s): Human T cell leukaemia virus type 1 (HTLV-1) is associated with adult T cell leukaemia (ATL), a malignant lymphoproliferative disease that infects CD4 T cells. It is not clear why the majority of HTLV-1-infected individuals remain asymptomatic carries (ACs) and a minority develop ATL. Cellular immune response has a critical role in ATL and destroys malign...

of April 14 , 2017 . This information is current as the Acute Phase Cytokine IL - 21 Recognizing Viral Antigens in the Context of Human B Cells Secrete Granzyme B When